Yu-Le dreams to perform on stage, but lymphoma makes it impossible. Her boyfriend Xiang-Yang desperately waits for the suitable bone marrow donor to appear. On the other hand, Yi-Rongives up her music career after her parents' death and works hard to support family. As her childhood sweetheart Jin-Ru comes back, happiness seems to finally arrive. However, working too hard triggers her leukemia. Facing life's difficulties, can these two music girls wait until the antidote to happiness?