Filmmaker Lucia Mauro presents a living portrait of the Italy-born saint that showcases her relevance in an ever-changing world. The Patron Saint of Immigrants and Hospital Administrators is explored as a fearless, roll-up-her-sleeves woman who, despite frail health, traveled the world at the turn of the 20th century to serve the less fortunate. It shows the environment in Lombardy, Italy that shaped her compassionate vision and includes interviews with individuals from all walks of life, who carry on Mother Cabrini's work today as the needs of immigrants and other populations continue to evolve.