"1,2,3, Once Again" depicts, in an experimental way, a number of sessions mediated by music (leaded by Luísa Brandão), in the context of therapeutic programs with People with Alzheimer. These interventions were part of the work carried by the team of the Day Area in Psychogeriatrics, created by Doctor Pedro Macedo, in the "Centro Hospitalar Psiquiátrico of Lisbon" (2013). To the human reality of the sessions the film adds, in an inclusive way, the possibility of daydreaming, by a less corporative work on sound and image.