Murielle Telio was born in New York City, New York, to parents, Janine (Sitbon), a clothing wholesaler, and Ike Telio, a financial analyst. Murielle was raised in New Orleans, Louisiana. She attended Tulane University. Telio then decided to move to Los Angeles and concentrate on acting and writing. She is a poet and a novelist and has written multiple screenplays. As an actress, she played "Ashley" on the HBO series, East Bound and Down, and as "Misty Mountains" in Shane Black's The Nice Guys. She has also appeared on Marvel's Agents of Shield and recurred on David Gordon Green and Steve Soderbergh's series, Red Oaks. She has also appeared in The Duff, and Game of Assassins.