Samantha Gail Weinstein was born on March 20, 1995 in Toronto, Canada. An actor since the age of six, she was best known for her roles as Heather in MGM's remake of Carrie (2013), Audrey in Jesus Henry Christ (2011), and Josephine in the TIFF award winning short film, Big Girl (2005). Big Girl also won Samantha the 2006 ACTRA award for Best Performance-Female. Having won the award at age ten, she was the youngest recipient to date.

Other notable film roles include Brooke in the independent feature, Reign (2015), Violet in The Rocker (2008), and young Hagar in Margaret Atwood's The Stone Angel (2007). Some of Samantha's television credits include guest roles on Being Erica, Less Than Kind, Copper, and Darknet. Darknet marked Samantha's second project with Canadian director Vincenzo Natali, the first being the independent feature, Haunter (2013). She was also an avid voice performer and had voiced numerous animated characters during her career.

As lead singer/songwriter and lead guitarist, Samantha founded the Toronto based, garage rock band, Killer Virgins, in April of 2016. On May 14th, 2023 Samantha died from ovarian cancer after bravely fighting for two and a half years. She died at Toronto's Princess Margaret Hospital surrounded by her loved ones.