Greg Vrotsos was born Gregory Nicholas Vrotsos in the Greater Boston town of Norwood, MA. His parents, Vaso, a hairdresser, and Nicholas, a carpenter and pizzeria owner, are from the Peloponesse region of Greece. After graduating from Norwood High School, Greg moved to Southern California. He briefly attended Marymount College before making the move to Los Angeles and studying acting under the Meisner technique. After a few years of study he began writing, directing, and acting in his own short films which eventually led to him finding work as an actor. Since then, he has worked and continues to work in Television and Film, ranging from drama to comedy.

Greg has had key roles in television shows such as Orange Is The New Black, Mayans MC, Twin Peaks, and Vinyl. In film, he was most recently seen alongside Keira Knightley in the Boston Strangler. He is a frequent collaborator of Dito Montiel, appearing in three of his films. Along with a resume that has had him acting opposite of some of the industry's top talent, Greg also works as a writer and director.