After decades in show business, character actor Conrad Janis came to prominence as Mindy's father on TV's Mork & Mindy (1978). Manhattan-born Janis was the son of renowned art dealer and clothing manufacturer Sidney Janis (1986-1989), and his wife Harriet (Grossman), who wrote books about jazz. He began acting as a 13 year old with a travelling stock company. Subsequently working as a radio actor, he went on to provide assorted voices, ranging from teens to middle aged men. He also had a small role in the 1945 Broadway play Dark of the Moon which was noticed by a Hollywood talent scout and paved the way to some freelance work in motion pictures, where he was featured as juvenile leads. In the early 50s, Janis segued into television while pursuing a separate career as a jazz trombonist, inspired by the music of Kid Ory. Having perfected his skills by studying under Cab Calloway alumni Tyree Glenn and Herbie Nichols, Janis fronted his own Dixieland/trad combo (Conrad Janis and His Tailgate Five) in the early 50s. By the late '70s, he had formed the Beverly Hills Unlisted Jazz Band which performed in many festivals and was often showcased on David Letterman's and Johnny Carson's late shows.

Janis acted in anthology TV dramas from as early as 1950, according to his account ultimately racking up some 700 appearances (many of them not recorded or otherwise lost to posterity). He toiled away in fairly minor parts until his breakout role as music store owner Fred McConnell in Mork & Mindy. In addition to numerous guest appearances, the balding Janis was also seen as a regular in the short-lived sitcom Quark (1977) (as philistine bureaucrat Otto Bob Palindrome) and in recurring roles on Cinayet Dosyası (1984) and Frasier (1993). True to his roots, he remained involved with the art world and with music education throughout his life.