Don DeFore toured the country in stock companies for several years before making his Broadway debut in 1938. In films since 1941, he occasionally played leads in B pictures, but was more often cast as the good-natured buddy of the hero or a likable but gullible character whom the hero has to bail out of trouble. DeFore found much more success on television, and was a regular in the hit series Hazel (1961) and The Adventures of Ozzie and Harriet (1952).