Isabella Castillo was born on December 23, 1994 in Havana, Cuba. She was born in a musical family, her mother Delia Diaz de Villegas was a known singer in the island. Her father, Jose Castillo is a drummer and her sister Giselle Castillo graduated from the university in Music Education. In 1997 she migrated to Belize City and months later she moved to Miami, Florida (USA). At the age of 5 years, she decided she wanted to sing in one of her mother's show, she blew them away with her powerful voice and small age. She took voice, dance and acting lessons. In 2007 she went to Madrid, Spain for a casting for the musical Ana Frank - Un Canto a la Vida. She got the part of Anne Frank and moved with her parents to Spain. She received the award Premio Gran Via for Best Revelation in a Musical. When the musical ended she came back to the United States and was casted to play the part of Andrea Giron in El Fantasma de Elena with Telemundo. After the end of this soap opera she was casted for Grachi and became the main character in the TV series Grachi for Nickelodeon. She won the Nickelodeon's Kids Choice Awards Mexico 2011 for Best Female Artist in a TV series. Right now she finished filming Grachi second season and is traveling through out Latin America with Grachi the Musical.