As a teenager, Nick Smyth was cast as a regular on the long-running CBC television series "Street Cents" in his hometown of Halifax, Nova Scotia. A show that was known for launching the careers of fellow Halifax natives Jonathan Torrens and Mike Clattenburg (Creator of the "Trailer Park Boys"); he stayed with the show for two seasons.

After performing stand-up comedy in and around Halifax, Nova Scotia for three years he moved to Toronto at age 20 where he worked briefly for Much Music. It was around this time that he was given a TV development deal for his own Saturday morning television series from the makers and producers of the popular TV series "This Is Daniel Cook". Meant to showcase Nick's unique comedic style; "Upload" was developed from the ground up exclusively in partnership with Sinking Ship Entertainment and TVO Kids. Also around this time he was signed on for a Pilot project being produced by Kevin Sullivan (creator and producer of "Road To Avonlea" and "Anne Of Green Gables")

In 2012 he was signed on to be a cast member and writer in the very last season of Much Music's highly popular television series "Video On Trial".

In 2013 he did the male lead on the award winning film "Somnolence" which went on to be presented at that years Cannes International Film Festival.

Also in 2013 he played the lead in Director Marcus Alqueres' hugely popular short film "The Flying Man" which went on to receive more than 20 million hits online as well as high praise from Marvel comics chief creative officer Joe Quesada. In 2015 a feature film deal with Chris Collins (writer and producer of "Sons Of Anarchy" and "The Wire") and Sony Pictures was made.