Born Isabella Calò in Mantua, she was forced to change her family name of Jewish origins to Bellini because of the racial laws. After winning a national contest for singers she entered EIAR, where she was active both as a solo singer and as a member of the "Trio Primavera" with Thea Prandi and Wilma Mangini. During and shortly after the war, Bellini devoted herself exclusively to the theater, working on stage with popular artists such as Totò, Renato Rascel, Walter Chiari and Umberto Spadaro. In 1948 she began working on radio as a presenter and entertainer. In 1954 she hosted the popular radio show "Il motivo in maschera" together with Mike Bongiorno and Lelio Luttazzi, and in the same year she debuted as a television presenter in "Italia. Nati per la musica". Bellini later gradually thinned out her appearances on media, focusing on dubbing.