Muzzi Loffredo was born on 5 February 1941 in Palermo, Sicily, Italy. She was an actress and director, known for Occhio nero, occhio biondo e occhio felino (1983), La certosa di Parma (1982) and İsa Eboli'de Durdu (1979). She was married to Ruggero Guarini. She died on 9 September 2017 in Rome, Lazio, Italy.