After her heart attack, Marianne Toeplitz should actually take it easy. But since the bus company Toeplitz-Reisen, her life's work, is threatened with bankruptcy, all of her energy is required. Marianne indignantly rejects her daughter Susanne's proposal to merge with the competition. There is also a lot of trouble privately: Susanne has booked a language holiday in England for her teenage daughter Nellie. The amorous Nellie is not at all enthusiastic about it, because she absolutely wants to visit her boyfriend in Rimini. Marianne remembers spending love holidays there as a young girl with a charming Italian - and so grandmother and granddaughter spontaneously set off for Rimini. Susanne is furious because she has already initiated the formalities at the bank. In the anxious anticipation of who will go down earlier: Marianne with her heart or the poorly repaired oldie bus, built in 1962, she drives after the two runaways together with her ex-husband Jan. Despite car breakdowns and traffic jams, the trip across the Alps will be unforgettable for everyone involved. Susanne and Jan mend their failed marriage, Nellie meets a nice Italian - and when Marianne meets her great love Giuseppe, she suddenly has the idea of her life .