The story is the bridges the gap of Assassin's Creed II and Assassin's Creed Brotherhood. After the destruction of Monteriggioni in the year 1500, Ezio met with Leonardo Da Vinci to gather information about the Pope's son, Cesare Borgia. Leonardo tells Ezio of Cesare's rise to power.

Assassin's Creed: Ascendance

Taking place after the events of Assassin's Creed: Revelations in the year 1524 in Tuscany, follow the retired Assassin Ezio Auditore as he teams up with Shao Jun during his final battles.