Keke is a young girl with a loving father and mother, as well as loyal friends. She is diagnosed with Rhabdomyosarcoma (a cancer of connective tissues), which is unusual at her age. After undergoing twenty-five sessions of chemotherapy, the once healthy and beautiful Keke finds herself sickly and bald, with a disfigured face. Although the treatment initially works, the cancer returns a year later. Doctors estimate that Keke has three months to live. To help her deal with her pain, she begins keeping a diary; through her writing she finds the strength to hold on for a year. As she begins to accept her fate, she writes a letter to God in her diary, asking that her family be kept safe.

A Small Letter To God

Bara Mahesa (Dimas Anggara), who wants to be a writer, is restless in the absence of any girlfriend. He then meets Velin Caliandra (Natasha Rizki), a junior that later become his girlfriend. But Velin is a spoiled girl and a source of irritation. Then comes Diandra Pramita (Alisia Rininta), a senior who can make Bara feels comfortable. But Diandra in fact is going to be a source of greater resentment.