Frictions develop when Yisroel "Izzy" Jonigkeyt, a Chassidic Jew from Crown Heights, travels to San Francisco to visit Polish-born Catholic friend Marek Wisniewski with the intent of discovering why a Bay Area art-world iconoclast named Harry Kierk seeks to destroy a lifetime's worth of his own work. As the visit progresses, Izzy and Marek discover for the first time that complex historical baggage impinges on their curious friendship and, soon, they begin to understand why Kierk is driven towards destruction. Continued encounters with Marek's vaguely anti-Semitic cousin Irek (who is their only gateway to contact Kierk) only compound these tensions.

Ezer Kenegdo

Sky-high housing costs, rents no one can pay, urban development, and street crime make life difficult for RV dwellers in Berkeley, California. City bureaucrats collaborate with real estate agents to gentrify neighborhoods forcing out already marginalized people living in cars, trucks, and RVs. With no more West to escape to, they contemplate turning back East. Sandy 1, the clan's Mother Teresa, beset with seizures, her nephew Rail, a young poet and tap dancer, traveling with his girlfriend Mitra on a motorcycle, look for clues to Arid Cut, a place in the desert where Rail might find Bert Neville, the father he never met. Ziggy and Travis, builders and jacks of all trades, think they might have a clue as the building site they're working is shut down by the city. Taylor is a rapper looking for gigs along the way with his eccentric agent, Wes and his stoner friend, Geoff. Lucille drives Uber and lives with her mother in a van. Herbie sells meth for Pinto, dealer and RV dweller, in order to keep his younger brother in school. Sandy 1 suddenly dies of a seizure and friends gather to mourn. In Sandy's honor, and to help Rail, they agree to head East on a search for Arid Cut.

Arid Cut

Eddie Huntly, an east coast radio personality, moves to San Francisco to marry Thea, the sister of his best friend Neil, a successful entrepreneur. Shortly before Eddie's arrival, Neil is found murdered in what the police surmise was a simple mugging gone awry. As the sullen Eddie steps in as interim host of his old friend Dean's late-night talk-radio show, he obsessively makes regular visits to the forested spot where Neil's corpse was found. One such visit unleashes a chain of unpredictable events that sends Eddie snooping into the life of a sleepwalking drifter with a mysterious past.