Days before Valentine's day and their wedding, Cindy Hunter, editor-in-chief of a tabloid and Damon Tuckland, a successful therapist encounter a strange plant that magically puts Cindy's mind in Damon's body and vice versa. Now the couple really finds out how the other half lives. In a series of comic mishaps at work, with relatives and at home, Cindy and Damon must become better people and figure out a way to reverse the "awkward" situation before their wedding or face a lifetime as each other. It's the ultimate body-swapping comedy with a heart that gives a brand-new meaning to the term "The Opposite Sex".